Scientific Program
| October 23(Wed) 08:30-10:10 |
Symposium 19 Cytokine Dynamics in T Helper Cell Immune Regulation |
Room A | |
|---|---|---|---|
| Chair(s) |
Joanna Groom (WEHI, AUS) Gap Ryol Lee (Sogang University, KOR) |
||
| 08:30-08:55 |
Cytokines reorganize the 3D genome interactions in T cells
Golnaz Vahedi (Univ. of Pennsylvania, USA) |
Abstract | |
| 08:55-09:20 |
Scratching exaggerates allergic inflammation and augments host defense via neurogenic mast cell activation
Daniel Kaplan (Univ. of Pittsburgh, USA) |
Abstract | |
| 09:20-09:45 |
Non-canonical regulation of IL-21 bioavailability and activity
Di Yu (The Univ. of Queensland, AUS) |
Abstract | |
| 09:45-09:57 |
A Th9-endotheliala activation loop promotes inflammatory cardiovascular disease (2024 ICIS-Regeneron New Investigator Awards for Excellence in Cytokine & Interferon Research)
Daniella M. Schwartz (University of Pittsburgh, USA) |
Abstract | |
| 09:57-10:09 |
TGF-beta differentially specifies TFH/TH17 and TFR/Treg cell fates in murine CD4+ T cells through c-Maf
Dirk Baumjohann (University Hospital Bonn, DEU) |
Abstract | |
| October 23(Wed) 08:30-10:10 |
Symposium 20 Cytokine-mediated Translational Approaches of Human Diseases |
Room B | |
|---|---|---|---|
| Chair(s) |
Simon Jones (The School of Medicine, Cardiff University, GBR) Chang-Hoon Kim (Yonsei University College of Medicine, KOR) |
||
| 08:30-08:55 |
Anti-T2 biologics in severe asthma
Ian Adcock (Imperial College London, GBR) |
Abstract | |
| 08:55-09:20 |
Role of CXCR6+CD4+ tissue-resident memory T cells in chronic allergic skin inflammation
Kenji Kabashima (Kyoto Univ., JPN) |
Abstract | |
| 09:20-09:32 |
A Clinical Trial Combining a Tumor Targeting Immunocytokine (PDS01ADC) and Enzalutamide without Testosterone Lowering Therapy in Biochemically Recurrent Prostate Cancer
Ravi Madan (National Cancer Institute, USA) |
Abstract | |
| 09:32-09:44 |
STAT3beta Represses Interferon Signaling and thereby Contributes to Favorable Outcomes in Acute Myeloid Leukemia
Sophie Edtmayer (Karl Landsteiner University of Health Sciences, AUT) |
Abstract | |
| 09:44-09:56 |
Interferon Signature with Allograft Inflammatory Factor-1 Predicts TNF Inhibitor Response in Ankylosing Spondylitis
Jeong Seok Lee (KAIST, KOR) |
Abstract | |
| October 23(Wed) 08:30-10:10 |
Symposium 21 Cytokine Drug Development (Partly Sponsored by Coherus) |
Room C | |
|---|---|---|---|
| Chair(s) |
Juan Mendoza (Univ Chicago, USA) Theresa LaVallee (Coherus BioSciences, USA) |
||
| 08:30-08:42 |
Evaluation of CD25-biased IL-2m activity on non-Treg populations in vitro and in vivo
Kelly Remedios (Gilead, USA) |
Abstract | |
| 08:42-08:54 |
Cell type-specific type I IFN antiviral response defines the neurotropism of Mpox virus
Oliver Harschnitz (Human Technopole, ITA) |
Abstract | |
| 08:54-09:06 |
Pharmacodynamic Biomarkers of BMS-986326, a Novel IL-2/CD25 Fusion Protein That Induces Highly Selective and Durable Expansion of Regulatory T Cells Following Administration in Healthy Volunteers
Eun Mi Hur (Bristol Myers Squibb, USA) |
Abstract | |
| 09:06-09:18 |
An Orthogonal IL-2/IL-2R-System Enhances Engineered T Cell Therapies Via a Highly Functional Synthetic Effector State and Obviates the Need for Lymphodepletion in Solid Tumors
PJ Aspuria (Synthekine, USA) |
Abstract | |
| 09:18-09:30 |
The combination of NT-I7 and hIL-2/TCB2c promotes the development of an immune-stimulatory tumor microenvironment that enhances the anti-tumor efficacy in combination with checkpoint inhibitors
Minji Lee (NeoImmuneTech Co., Ltd., KOR) |
Abstract | |
| 09:30-09:42 |
Development of Tuneable Cytokines via Tumor Stroma Sequestering Linkers
Phillip S. Kim (Trutino Biosciences, USA) |
Abstract | |
| 09:42-09:54 |
A Novel Nanobody Based IL-18 Surrogate Cytokine Agonist, Used Alone or Combined with Immune Checkpoint Inhibitors, Demonstrated Synergistic Tumor Suppression in Xenograft mouse model
Yakun Wan (Shanghai Novamab Biopharmaceuticals Co., Ltd., CHN) |
Abstract | |
| October 23(Wed) 10:10-10:40 |
Coffee Break | ||
|---|---|---|---|
| October 23(Wed) 10:40-11:10 |
Industry 5 Inflammasome-activated Cytokines in Human Diseases (BMS) |
Room A | |
|---|---|---|---|
| Chair(s) | Aisling O’Hara Hall (Bristol Myers Squibb, USA) | ||
| 10:40-11:10 |
Inflammasome-activated cytokines in human diseases
Scott Canna (University of Pennsylvania Perelman School of Medicine, USA) |
Abstract | |
| October 23(Wed) 10:40-11:10 |
Industry 6 Filgotinib in the Treatment Algorithm of Rheumatoid Arthritis (Eisai Korea) |
Room B | |
|---|---|---|---|
| Chair(s) | Eun Young Lee (Seoul National University Hospital, KOR) | ||
| 10:40-11:10 |
Filgotinib in the treatment algorithm of rheumatoid arthritis
Jung Hee Koh (The Catholic Univ. of Korea, College of Medicine, KOR) |
Abstract | |
| October 23(Wed) 11:10-12:00 |
Lightning Talks 7 Cytokines and Human Diseases |
Room A | |
|---|---|---|---|
| Chair(s) |
Erik Lubberts (Erasmus MC, University Medical Center, NLD) Seokchan Hong (University of Ulsan College of Medicine, Asan Medical Center, KOR) |
||
| 11:10-11:18 |
CD25lowFoxp3+ T cells in small intestinal lamina propria contribute to rheumatoid arthritis pathogenicity by promoting conversion into pro-inflammatory Th17 cells
Sangwon Lee (College of Medicine, Gyeongsang National University, KOR) |
Abstract | |
| 11:18-11:26 |
Pathophysiology of Dupilumab-Associated Head and Neck Dermatitis: An Integrated Analysis of Microbiome and Cytokinome
Wanjin Kim (Yonsei University College of Medicine, KOR) |
Abstract | |
| 11:26-11:34 |
Novel Application of Established Arthritis Models Identifies Cytokine-Regulated Perturbations in Ocular Immune Homeostasis that Coincide with Arthritic Flares
Simon Eastham (University of Bristol, UK) |
Abstract | |
| 11:34-11:42 |
HLA Class I-Downregulated Senescent Epidermal Basal Cells Orchestrate Skin Pathology in Systemic Lupus Erythematosus
Sena Yamamoto (Hokkaido University, JPN) |
Abstract | |
| 11:42-11:50 |
Data Mining of IFNgamma-induced macrophage and Atherosclerotic Plaque Transcriptomes predicts a macrophage-specific role of STAT1 in human atherosclerosis
Natalia Lopacinska (Human Molecular Genetics Research Unit AMU, Poland) |
Abstract | |
| 11:50-11:58 |
Investigation of the Pathogenesis of GM-CSF Autoantibodies Isolated from Patients with Cryptococcus Infection
Yu-Fang Lo (Chang-Gung University, Taiwan) |
Abstract | |
| October 23(Wed) 11:10-12:00 |
Lightning Talks 8 Cytokine Modulation of Adaptive Immunity |
Room B | |
|---|---|---|---|
| Chair(s) |
Dirk Baumjohann (University Hospital Bonn, DEU) Youn Soo Choi (Seoul National University College of Medicine, KOR) |
||
| 11:10-11:18 |
Deciphering the regulation of IL-2 signaling in T cells
Suyasha Roy (National Heart, Lung and Blood Institute, National Institutes of Health, USA) |
Abstract | |
| 11:18-11:26 |
Epigenetic Regulators Of Clonal Hematopoiesis Control CD8 T cell Stemness During Immunotherapy
Tae Gun Kang (ST JUDE CHILDRENS RESEARCH HOSPITAL, USA) |
Abstract | |
| 11:26-11:34 |
Interferon-Mediated Regulation of B-cell Responses to Viral Infection
Alana Kirn (Monash University, AUS) |
Abstract | |
| 11:34-11:42 |
Bystander Th17 Activation And Its Functional Impact On Heterologous Challenge
Shweta Sabu (University of Zurich, Switzerland) |
Abstract | |
| 11:42-11:50 |
The Multifaceted Nature of Tissue-Resident Memory T Cells in Healthy Organs
Hyun Jae Lee (The University of Melbourne, AUS) |
Abstract | |
| 11:50-11:58 |
CIC-ATXN1L complex regulates marginal zone B cell development and sepsis via ETV4-Notch axis
Jongseok Park (POSTECH, KOR) |
Abstract | |
| October 23(Wed) 11:10-12:00 |
Lightning Talks 9 Cytokine Signaling and Regulation |
Room C | |
|---|---|---|---|
| Chair(s) |
Rachel Gottschalk (University of Pittsburgh, USA) Ina Rudloff (Hudson Institute of Medical Research, AUS) |
||
| 11:10-11:18 |
Preclinical Development of a 3rd Generation Interleukin-2 Targeted to Inflammatory Sites (IL-2IT)
Monica Cuevas Martinez (Sorbonne University, FRA) |
Abstract | |
| 11:18-11:26 |
The alpha 2,8-disialyl Motif Modulates B-cell Receptor Signaling
Ho-Yang Tsai (Academia Sinica, Taiwan) |
Abstract | |
| 11:26-11:34 |
Piezo1-mediated Mechanotransduction shapes ILC2s responses and Lung inflammatory pathways.
MinYeong Lim (Seoul National University, College of Medicine, KOR) |
Abstract | |
| 11:34-11:42 |
IL-12 Signaling in Regulatory T Cells: like Protein Powder in Bodybuilding
Anna Estrada Brull (University of Zurich, Switzerland) |
Abstract | |
| 11:42-11:50 |
IFI16 Regulates Cytokine-induced Responses in Human Keratinocytes Independent of a Role in DNA Sensing.
Marcin Baran (Trinity College Dublin, IRE) |
Abstract | |
| 11:50-11:58 |
Modeling human mutations in mice reveals that a single amino acid in the STAT5B SH2 domain is critical for cytokine-induced enhancer activity.
Hye Kyung Lee (US National Institute of Health (NIH), USA) |
Abstract | |
| October 23(Wed) 12:00-13:30 |
Lunch Break | ||
|---|---|---|---|
| October 23(Wed) 13:30-14:30 |
Keynote 2 | Room A | |
|---|---|---|---|
| Chair(s) | Sarah Gaffen (University of Pittsburgh, USA) | ||
| 13:30-14:30 |
Nucleoside modified mRNA-LNP therapeutics
Drew Weissman (Univ. of Pennsylvania, USA) |
Abstract | |
| October 23(Wed) 14:30-15:00 |
Closing Session | Room A | |
|---|---|---|---|
|
Conference highlights & Closing remarks
|
|||
|
Invitation to Cytokines 2025
|
|||
| October 23(Wed) 15:30-16:30 |
Transportation | ||
|---|---|---|---|
| October 23(Wed) 16:30-21:00 |
Gala Dinner | ||
|---|---|---|---|
- Cytokines 2024 & KAI 2024 Secretariat
- Hosted by
-
- Sponsored by
-
Copyright ⓒ Cytokines 2024 & KAI 2024 Secretariat. All Rights Reserved.